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The most frequent AEs (≥2% in any treatment group) that occurred more often in the ritlecitinib groups than placebo and were dose-related included diarrhea, acne, urticaria, rash, and dizziness.21Table 2 lists AEs that occurred in ≥5% of patients in any treatment group within the all-exposure cohort.25 Adverse events of special interestInfections The incidence rate (IR) of serious infections was low across the ALLEGRO program
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35% Increase in GSH 6-month, high-dose clinical trial 2× NK cell activity Immune strengthening 500+ reactions Cellular processes Essential cofactor 3 amino acids Tripeptide Glu-Cys-Gly 54 topics Major clinical trial 6-month clinical study How does Glutathione work